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1

Serum HBeAg quantitation during antiviral therapy for chronic hepatitis B

Heijtink, Rudolf A., Kruining, Johannes, Honkoop, Pieter, Kuhns, Mary C., Hop, Wim C. J., Osterhaus, Albert D. M. E, Schalm, Solko W.

Journal:

Journal of Medical Virology

Year:

1997

Language:

english

File:

PDF, 92 KB

english, 1997

2

Characteristics of the early phase of chronicity in acute hepatitis B infection

Heijtink, R.A., Paulij, W., van Roosmalen, M., Hellings, J.A., Niesters, H.G.M., Schalm, S.W., Osterhaus, A.D.M.E.

Journal:

Journal of Medical Virology

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

3

Quantitative relationship between HBeAg and DNA polymerase activity in sera from patients with chronic active hepatitis during a three-month period

R. A. Heijtink, M. van der Waart, W. Weimar, S. W. Schalm, N. Masurel

Journal:

Journal of Medical Virology

Year:

1980

Language:

english

File:

PDF, 420 KB

english, 1980

4

Interferon-alpha therapy for chronic hepatitis B: Early response related to pre-treatment changes in viral replication

R.A. Heijtink, H.L.A. Janssen, W.C.J. Hop, A.D.M.E. Osterhaus, S.W. Schalm

Journal:

Journal of Medical Virology

Year:

2001

Language:

english

File:

PDF, 75 KB

english, 2001

5

Spontaneous disappearance of viral replication and liver cell inflammation in HBsAg-positive chronic active hepatitis: Results of a placebo vs. interferon trial

Solko W. Schalm, Rudolf A. Heijtink

Journal:

Year:

1982

Language:

english

File:

PDF, 471 KB

english, 1982

6

Hepatitis B Vaccination in Down's Syndrome and Other Mentally Retarded Patients

Rudolf A. Heijtink, Pieter De Jong, Solko W. Schalm, Nic Masurel

Journal:

Year:

1984

Language:

english

File:

PDF, 503 KB

english, 1984

7

HBV-DNA detection by gene amplification in acute hepatitis B

Wim G. V. Quint, Inge de Bruijn, Hans Kruining, Dr. Rudolf A. Heijtink

Journal:

Year:

1990

Language:

english

File:

PDF, 506 KB

english, 1990

8

Interferon-α and zidovudine combination therapy for chronic hepatitis B: Results of a randomized, placebo-controlled trial

Harry L. A. Janssen, Luuk Berk, Rudolf A. Heijtink, Fiebo J. W. Ten Kate, Solko W. Schalm

Journal:

Year:

1993

Language:

english

File:

PDF, 630 KB

english, 1993

9

Anti-hepatitis B virus activity of a mixture of two monoclonal antibodies in an “inhibition in solution” assay

Rudolf A. Heijtink, Johannes Kruining, Yvonne A. M. Weber, Robert A. de Man, Solko W. Schalm

Journal:

Year:

1995

Language:

english

File:

PDF, 669 KB

english, 1995

10

Administration of a human monoclonal antibody (TUVIRUMAB) to chronic hepatitis B patients pre-treated with lamivudine: monitoring of serum TUVIRUMAB in immune complexes

R.A. Heijtink, A.B. van Nunen, P. van Bergen, L. Östberg, A.D.M.E. Osterhaus, R.A. de Man

Journal:

Journal of Medical Virology

Year:

2001

Language:

english

File:

PDF, 198 KB

english, 2001

11

Co-occurrence of HBsAg and anti-HBs: Two consecutive infections or a sign of advanced chronic liver disease?

Dr. R. A. Heijtink, J. Van Hattum, S. W. Schalm, N. Masurel

Journal:

Journal of Medical Virology

Year:

1982

Language:

english

File:

PDF, 558 KB

english, 1982

12

Detection of integration during active replication of hepatitis B virus in the liver

P. J. Boender, S. W. Schalm, Dr. R. A. Heijtink

Journal:

Journal of Medical Virology

Year:

1985

Language:

english

File:

PDF, 505 KB

english, 1985

13

Low-dose (2 μg) hepatitis B vaccination in medical students: Comparable immunogenicity for intramuscular and intradermal routes

Dr. R. A. Heijtink, R. M. Knol, S. W. Schalm

Journal:

Journal of Medical Virology

Year:

1989

Language:

english

File:

PDF, 306 KB

english, 1989

14

Long-term immune reactivity to pre-S(2)-antigen after acute hepatitis B infection

Dr. Rudolf A. Heijtink, Gerrie A. de Wilde, Jan van Hattum, Solko W. Schalm

Journal:

Journal of Medical Virology

Year:

1989

Language:

english

File:

PDF, 521 KB

english, 1989

15

Significance of isolated hepatitis B core antibodies detected by enzyme immunoassay in a high risk population

Dr. A. C. M. Kroes, W. G. V. Quint, R. A. Heijtink

Journal:

Journal of Medical Virology

Year:

1991

Language:

english

File:

PDF, 454 KB

english, 1991

16

Quantitative assessment of hepatitis B virus DNA in chronic hepatitis B: comparison of two solution hybridization assays

Harry L. A. Janssen, Yvonne A. M. Schoenmaker-Weber, Hans Kruining, Solko W. Schalm, Rudolf A. Heijtink

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 530 KB

english, 1993

17

Immunogenicity of 20 μg of recombinant DNA hepatitis B vaccine in healthy neonates: A comparison of three different vaccination schemes

R. Del Canho, P. M. Grosheide, M. Voogd, W. M. Huisman, R. A. Heijtink, Dr. S. W. Schalm

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 558 KB

english, 1993

18

Rapid detection of hepatitis C virus RNA by direct capture from blood

Leen-Jan van Doom, Bernhard Kleter, Jolanda Voermans, Geert Maertens, Hans Brouwer, Ruud Heijtink, Wim Quint

Journal:

Journal of Medical Virology

Year:

1994

Language:

english

File:

PDF, 753 KB

english, 1994

19

Rapid genotyping of hepatitis C virus RNA-isolates obtained from patients residing in Western Europe

G. E. M. Kleter, L. J. van Doorn, L. Stuyver, G. Maertens, J. T. Brouwer, S. W. Schalm, R. A. Heijtink, W. G. V. Quint

Journal:

Journal of Medical Virology

Year:

1995

Language:

english

File:

PDF, 883 KB

english, 1995

20

Quantitative measurement of HBeAg in chronic hepatitis B: A comparison between a radioimmunoassay a fluorescence ELISA and a chemiluminescence ELISA

Dr. R. A. Heijtink, J. Snobl, J. Kruining, C. Kerkhof-Los, R. A. de Man, H. L. A. Janssen, S. W. Schalm

Journal:

Journal of Medical Virology

Year:

1995

Language:

english

File:

PDF, 478 KB

english, 1995

21

Genetic characteristics of hepatitis B virus genotypes as a factor for interferon-induced HBeAg clearance

Jinlin Hou, Ralf Schilling, Harry L. A. Janssen, Bettina E. Hansen, Rudolf Heijtink, Erwin Sablon, Roger Williams, George K.K. Lau, Solko W. Schalm, Nikolai V. Naoumov

Journal:

Journal of Medical Virology

Year:

2007

Language:

english

File:

PDF, 224 KB

english, 2007

22

Characterization of a human monoclonal antibody obtained after immunization with plasma vaccine and a booster with recombinant-DNA hepatitis B vaccine

R.A. Heijtink, J. Kruining, P. van Bergen, S. de Rave, J. van Hattum, M. Schutten, A.D.M.E. Osterhaus

Journal:

Journal of Medical Virology

Year:

2002

Language:

english

File:

PDF, 204 KB

english, 2002

23

Interferon-α therapy in chronic hepatitis B: early monitoring of hepatitis B e antigen may help to decide whether to stop or to prolong therapy

Heijtink, Janssen, Hop, Osterhaus, Schalm

Journal:

Journal of Viral Hepatitis

Year:

2000

Language:

english

File:

PDF, 128 KB

english, 2000

24

Passive immunization of chronic hepatitis B patients on lamivudine therapy: a feasible issue?

A. B. Van Nunen, R. A. De Man, R. A. Heijtink, A. C. T. M. Vossen, S. W. Schalm

Journal:

Journal of Viral Hepatitis

Year:

2002

Language:

english

File:

PDF, 403 KB

english, 2002

25

Early invasive prenatal diagnosis in HBsAg-positive women

P. M. Grosheide, H. W. P. Quartero, Professor Dr S. W. Schalm, R. A. Heijtink, G. C. M. L. Christiaens

Journal:

Prenatal Diagnosis

Year:

1994

Language:

english

File:

PDF, 497 KB

english, 1994

26

Hepatitis B vaccination in drug addicts and Down's syndrome patients

R. A. Heijtink, J. Kruining, P. Jong, S. W. Schalm, N. Masurel

Journal:

Antonie van Leeuwenhoek

Year:

1983

Language:

english

File:

PDF, 115 KB

english, 1983

27

Vaccination against hepatitis B: prescreening and follow-up by an ELISA detecting both HBsAg and anti-HBs

L. Kuijpers, R. A. Heijtink, A. Jacobs, G. Wolters, J. Kruining

Journal:

Antonie van Leeuwenhoek

Year:

1983

Language:

english

File:

PDF, 42 KB

english, 1983

28

Prevaccination screening for hepatitis B in the Netherlands: a pilot study for vaccination advice

Journal:

Antonie van Leeuwenhoek

Year:

1985

Language:

english

File:

PDF, 89 KB

english, 1985

29

Co-occurrence of HBsAg and heterotypic anti-HBs

R. A. Heijtink, J. Hattum, S. W. Schalm

Journal:

Antonie van Leeuwenhoek

Year:

1981

Language:

english

File:

PDF, 49 KB

english, 1981

30

Influenza vaccination in HBsAg positive chronic active hepatitis patients treated with interferon

R. A. Heijtink, N. Masurel, W. Weimar, S. W. Schalm

Journal:

Medical Microbiology and Immunology

Year:

1980

Language:

english

File:

PDF, 368 KB

english, 1980

31

Quantitative HBV DNA levels as an early predictor of nonresponse in chronic HBe-antigen positive hepatitis B patients treated with interferon-alpha

A. A. Van Der Eijk, H. G. M. Niesters, B. E. Hansen, R. A. Heijtink, H. L. A. Janssen, S. W. Schalm, R. A. De Man

Journal:

Journal of Viral Hepatitis

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

32

Differential effects of fibroblast and leucocyte interferon in HBsAg positive chronic active hepatitis

W. WEIMAR, R. A. HEIJTINK, S. W. SCHALM, H. SCHELLEKENS

Journal:

European Journal of Clinical Investigation

Year:

1979

Language:

english

File:

PDF, 362 KB

english, 1979

33

Hepatitis B vaccination of haemodialysis patients: randomized controlled trial comparing plasma-derived vaccine with and without pre-S antigen

M. B. L. SMIT-LEIJS, P. KRAMER, R. A. HEIJTINK, W. C. J. HOP, S. W. SCHALM

Journal:

European Journal of Clinical Investigation

Year:

1990

Language:

english

File:

PDF, 501 KB

english, 1990

34

Hepatitis B vaccination of haemodialysis patients: randomized controlled trial comparing plasma-derived vaccine with and without pre-S2 antigen

M. B. L. SMIT-LEIJS, P. KRAMER, R. A. HEIJTINK, W. C. J. HOP, S. W. SCHALM

Journal:

European Journal of Clinical Investigation

Year:

1990

Language:

english

File:

PDF, 500 KB

english, 1990

35

Hepatitis B surface antigen (HBsAg) derived from yeast cells (Hansenula polymorpha) used to establish an influence of antigenic subtype (adw2, adr, ayw3) in measuring the immune response after vaccination

R.A Heijtink, P van Bergen, K Melber, Z.A Janowicz, A.D.M.E Osterhaus

Journal:

Year:

2002

Language:

english

File:

PDF, 156 KB

english, 2002

36

Anti-HIV and Anti-HBV Activity and Resistance Profile of 2′,3′-Dideoxy-3′-Thiacytidine (3TC) and Its Arylphosphoramidate Derivative CF 1109

Jan Balzarini, O. Wedgwood, J. Kruining, Heidi Pelemans, R. Heijtink, Erik De Clercq, C. McGuigan

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 141 KB

english, 1996

37

Influence of perceived psychological stress and distress on antibody response to low dose rDNA hepatitis B vaccine

L. Jabaaij, P.M. Grosheide, R.A. Heijtink, H.J. Duivenvoorden, R.E. Ballieux, A.J.J.M. Vingerhoets

Journal:

Journal of Psychosomatic Research

Year:

1993

Language:

english

File:

PDF, 763 KB

english, 1993

38

Hepatitis C virus genotype: what does it tell us?

G.E.M. Kleter, J.T. Brouwer, L.J. von Doorn, W.G.V. Quint, S.W. Schalm, R.A. Heijtink

Journal:

The Netherlands Journal of Medicine

Year:

1995

Language:

english

File:

PDF, 139 KB

english, 1995

39

Conversion of 2′,3′-dideoxyadenosine (ddA) and 2′,3′-didehydro-2′,3′-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus

Jan Balzarini, Johannes Kruining, Orson Wedgwood, Christophe Pannecouque, Stefano Aquaro, Carlo-Federico Perno, Lieve Naesens, Myriam Witvrouw, Rudolf Heijtink, Erik De Clercq, Christopher McGuigan

Journal:

Year:

1997

Language:

english

File:

PDF, 563 KB

english, 1997

40

Anti-HBs after hepatitis B immunization with plasma-derived and recombinant DNA-derived vaccines: binding to mutant HBsAg

R.A Heijtink, P van Bergen, M.H van Roosmalen, C.M.G Sünnen, W.P Paulij, S.W Schalm, A.D.M.E Osterhaus

Journal:

Year:

2001

Language:

english

File:

PDF, 203 KB

english, 2001

41

Anti-HBs levels after hepatitis B immunisation depend on test reagents: routinely determined 10 and 100 IU/l seroprotection levels unreliable

R.A Heijtink, P.M Schneeberger, B Postma, W Crombach

Journal:

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

42

Ten-year neonatal hepatitis B vaccination program, the Netherlands, 1982–1992: protective efficacy and long-term immunogenicity

R. del Canho, P.M. Grosheide, J.A. Mazel, R.A. Heijtink, W.C.J. Hop, L.J. Gerards, G.C. de Gast, W.P.F. Fetter, J. Zwijneberg, S.W. Schalm

Journal:

Year:

1997

Language:

english

File:

PDF, 901 KB

english, 1997

43

Anti-HBs characteristics after hepatitis B immunisation with plasma-derived and recombinant DNA-derived vaccines

R.A. Heijtink, P. van Bergen, W.P. Paulij, R.A. de Man, A.D.M.E. Osterhaus

Journal:

Year:

2000

Language:

english

File:

PDF, 226 KB

english, 2000

44

Nucleosomal fragments in serum may directly reflect cell-mediated cytotoxic activity in vivo

Piet J. Boender, Ruud A. Heijtink, Jan-Albert Hellings

Journal:

Clinical Immunology and Immunopathology

Year:

1989

Language:

english

File:

PDF, 1.97 MB

english, 1989

45

Detection of HBV-DNA in liver biopsy and serum: Its significance in the selection of hepatitis B patients for antiviral therapy

R.A. Heijtink, P. Smal, F.J. ten Kate, J. Kruining, S.W. Schalm

Journal:

Antiviral Research

Year:

1987

Language:

english

File:

PDF, 660 KB

english, 1987

46

Anti-pre-S(2) analysis after hepatitis B vaccination in haemodialysis patients

R.A. Heijtink, G.A. de Wilde, J. Kruining, M.B.L. Smit-Leijs, S.W. Schalm

Journal:

Antiviral Research

Year:

1989

Language:

english

File:

PDF, 846 KB

english, 1989

47

Zidovudine inhibits hepatitis B virus replication

Luuk Berk, Solko W. Schalm, Rudolf A. Heijtink

Journal:

Antiviral Research

Year:

1992

Language:

english

File:

PDF, 413 KB

english, 1992

48

Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) on human and duck hepatitis B virus infection

R.A. Heijtink, G.A. De Wilde, J. Kruining, L. Berk, J. Balzarini, E. De Clercq, A. Holy, S.W. Schalm

Journal:

Antiviral Research

Year:

1993

Language:

english

File:

PDF, 873 KB

english, 1993

49

Measurement of HBsAg to monitor hepatitis B viral replication in patients on α-interferon therapy

Harry L.A. Janssen, Coby J. Kerhof-Los, Rudolf A. Heijtink, Solko W. Schalm

Journal:

Antiviral Research

Year:

1994

Language:

english

File:

PDF, 354 KB

english, 1994

50

Hepatitis B reactivation after lamivudine

P. Honkoop, R.A. de Man, R.A. Heijtink, S.W. Schalm

Journal:

Year:

1995

Language:

english

File:

PDF, 318 KB

english, 1995

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